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  • ISBN: 9780122204319
  • ISBN10: 012220431X

Analysis of Triplet Repeat Disorders

by D.C. Rubinsztein

  • List Price: $205.00
  • Binding: Hardcover
  • Publisher: Academic Pr
  • Publish date: 12/01/1999
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Description: The clinical picture of diseases caused by trinucleotide repeats, such as fragile X syndrome, myotonic dystrophy, Huntington's disease, and forms of spinocerebella ataxia, provides the starting point for this authoritative review volume. The book proceeds to integrate the current understanding of the molecular pathologies of these diseases, their genotype-phenotype relationships, the mutational processes involved, and the laboratory and clinical issues relating to genetic testing for these disorders. Clinicians and researchers in genetics, neuroscience, pediatrics, and psychiatry will all benefit from the comprehensive overviews contributed by recognized experts.
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