Description: Introduction to the principles of toxicology (D.L. Eaton, E.P. Gallagher). Exposure analysis and its assessment (P.J. Lioy). Toxicokinetics: oral exposure and absorption of toxicants (C.T. Walsh). Toxicokinetics: inhalation exposure and absorption of toxicants (M.A. Medinsky, P.M. Schlosser, B. Asgarian). Toxicokinetics: dermal exposure and absorption of toxicants (R.C. Wester, H.I. Maibach). Toxicokinetics: distribution of toxicants (E.J. O'Flaherty). Toxicokinetics: biotransformation of toxicants (G.L. Kedderis). Toxicokinetics: routes of elimination (D.E. Rickert). Toxicokinetics: concepts of dose (A.R. Dahl). Toxicokinetics: modeling disposition (G. Johanson). Toxicologic interactions of chemical mixtures (R.S.H. Yang). Experimental models for the investigation of toxicological mechanisms (D. Acosta, R.L. Grant, M.A. Smith). Cytolethality: necrosis vs. apoptosis (M. Treinen Moslen, A. Badakumaran). Mitogenesis (R.C. Cattley, B.G. Lake). The calcium messenger system (J.G. Pounds, M.J. McCabe). Mechanisms: free radicals and reactive oxygen species (J.P. Kehrer). DNA-reactive agents (A. Dipple). Risk assessment (J.V. Rodricks).

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