In Mutant Message Down Under, Marlo Morgan entranced readers with the story of a woman's unexpected four-month walkabout through the Australian outback with a tribe of nomadic aboriginals. The dramatic personal transformation she relates and the life-enhancing message from the 50,000-year-old aboriginal culture affected and inspired readers around the world.

In her new novel, Morgan unveils more aboriginal worldview through the story of aboriginal twins who grow up apart. A boy is adopted by an American family and raised in the United States with little sense of who he really is or of his cultural heritage. His sister is sent to an orphanage in Australia where she learns nothing of aboriginal culture and encounters continual racism. After a series of shattering losses, she strikes out into the desert, the land of her ancestors, where she discovers the spiritual truths that have been missing in her life. Becoming a "runner between worlds", she begins working as a political activist for aboriginal rights and a champion of the rights of adults who were taken from their native culture as children.

Her life's work brings her into contact with her brother, but at first neither is aware of their true relationship. The twins grow and change as they share their experiences with one another, and their journey teaches readers invaluable lessons about the quest forenlightenment and identity. Through their shared experiences of brother and sister, the reader gains deep insight and appreciation for the nomadic, primitive mind.