All of Louie's and Temple's allies and enemies converge on the case when a big-game hunter is found dead with only a leopard for company. And the fun really begins when the unofficial investigators learn that the leopard is Osiris, a performing Big Cat who was kidnapped from his magician owner only days before the murder.

Add to the mix a woman who's been surgically altered to resemble a Big Cat, a group of Las Vegas high-rollers who've been paying big bucks to illegally hunt big game at the victim's ranch, and a cadre of ardent animal rights protesters, determined to stop the illegal killing at any price, even their own lives... and anything can happen.