The Sinister Six attack, led by your archenemy, Dr. Octopus! You must face and defeat the Chameleon, the Hobgoblin, Mysterio, the Shocker, and the Vulture. Then you must overcome Doc Ock himself-- the one man who knows there's connection between Peter Parker and Spider-Man!

Your adventure starts on a movie set when a stunt goes horribly wrong. A stuntman is about to fall from the top of a building. As Spider-Man, you swing over to the rescue. But you swing to the wrong building, and the man almost dies! Your spider-sense has betrayed you. Why?

Against the Sinister Six, you need all your spider-powers working at their peak. Will you be able to defend Mary Jane when the villains attack? Or will you stay away until your powers return?

The choice is up to you, for you are Spider-Man!