Description: In recent years there have been several outbreaks throughout the world of multidrug resistant infections in large urban centers. Increasingly, antibiotic resistance is becoming a routine occurrence among practicing physicians. To fight against this resistance it is essential to understand the drug resistance mechanisms and to be able to detect the presence of resistance and its impact in the medical practice. Antibiotic Resistance Methods and Protocols outlines the mechanisms by which microbes become resistant to antibiotics and reviews practical methods for identifying and studying resistance in the clinical laboratory. This book presents epidemiological methods to track resistant pathogens. There is a strong emphasis on M. tuberculosis and S. pneumoniae, however the methods are also readily adaptable to other problem organisms. The protocols in this book will enable you to develop and implement new diagnostic and epidemiological techniques as well as to master the biological principles of antimicrobial resistance.

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