Metabolic Engineering Principles and Methodologies
- Binding: Hardcover
- Publisher: Academic Pr
- Publish date: 09/01/1998
The first part of Metabolic Engineering is a comprehensive review of cellular metabolism, including metabolic pathway regulation, stoichiometries, material balances, and models of cellular reactions. The result is a quantitative picture of metabolic biochemistry. The next part deals with pathway construction, stoichiometry, kinetics and thermodynamics. The key topics of pathway fluxes and flux control are examined in terms of metabolic flux analysis and metabolic control analysis. Pathway thermodynamics begins with an application of classical thermodynamics to sequences of reactions and concludes with the use of thermokinetics and irreversible thermodynamics to the description of pathway control. A glossary of biological terms and a minimum of mathematical complexity will facilitate use of the book by a broad spectrum of biochemists, molecular biologists, microbiologists, and biochemical/biomedical engineers.
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