Description: "This book is intended for the wide range of biologists interested in using the 'Two-Hybrid System' to identify proteins that interact. . . . Part I contains 4 chapters that describe the most common variations of the two-hybrid system, complete with details about plasmid structures and yeaststrain genotypes. There is sufficient information in these chapters for the average molecular biologist to implement the technique. . . . This book is a great resource for beginners as well as those who already use this technique, because each chapter contains its own methods section. This allowsone to compare strategies that have evolved separately in different labs. Furthermore, the book was edited by Stanley Fields, the inventor of the Two-Hybrid System, and the chapters were written by the workers who helped refine the methodology. It is a useful guide written by successfulpractitioners."--The Quarterly Review of Biology

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