Description:
The refinement of a chemical process to the point where it becomes both cost and time efficient can be seen as "art." In a competitive environment where pharmaceutical companies are under ever increasing pressure to bring new drugs more quickly to the market, ways need to be found to provide bulk supplies of drug candidates as quickly as possible and to design manufacturing routes, which are robust, economical and environmentally firendly. This monograph is divided into 9 chapters, each one concentrating on a single class of drug candidates of chemistry development and describing the routes explored and the optimizations made to each drug candidate, inluding the discovery of applicable new chemistry and the elucidation of reaction mechanism. From the contents: Efairenz®, a Non-Nucleoside Reverse Transciptase Inhibitor (NNRTI), and a Previous Structurally Related Development Candidate CCR5 Receptor Antagonist 5 -Reductase Inhibitors - The Finsteride Story Rizatriptan (Maxalt®): A 5-HT1D Receptor Agonist SERM: Selective Estrogen Receptor Modulator HIV Integrase Inhibitor: Raltegravir Cyclopentane-Based NK1 Receptor Antagonist Glucokinase Activator CB1R Inverse Agonist - Taranabant
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Product notice
Returnable at the third party seller's discretion and may come without consumable supplements like access codes, CD's, or workbooks.
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HPB-Diamond
Very Good
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$11.23
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Hennessey + Ingalls
Very Good |
$22.50
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ErgodeBooks
Good |
$22.98
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Kenneth Mallory, ABAA
Very Good
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$28.12
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ZENO'S
Very Good |
$35.43
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Bonita
Good
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$42.68
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ErgodeBooks
New |
$83.50
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GridFreed
New |
$114.36
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Bonita
New
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$130.87
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