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Drug Development Molecular Targets for Gi Diseases

by Timothy S. Gaginella

  • ISBN: 9780896035898
  • ISBN10: 0896035891

Drug Development Molecular Targets for Gi Diseases

by Timothy S. Gaginella

  • Binding: Hardcover
  • Publisher: Humana Pr Inc
  • Publish date: 09/01/1999
  • ISBN: 9780896035898
  • ISBN10: 0896035891
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Description: Critically reviews the many promising new areas of gastrointestinal pharmacology at the molecular level. Key chapters discuss such major themes as cyclooxygenase-2 inhibitors, the complexities of nitric oxide pathways in the gut, and the influence of cytokines on inflammatory bowel disease, as well as new opportunities for pharmacotherapy, including peptide growth factors achykinins-particularly substance P and neurokinins-cholecystokinin receptors, and serotonin. Also examined as possible sites for treating motility disorders and visceral pain are the opioid receptors residing in the gut, and the H3-receptor agonists for treating gut inflammation and pain. Drug Development: Molecular Targets for Gastrointestinal Disease provides a comprehensive review of today's molecular pharmacological approaches to the discovery and development of novel drugs for gastrointestinal and liver diseases.
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