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Gene Therapeutics: Methods and Applications of Direct Gene Transfer

by Wolff, J. A. A Wolff, Jon A.

Gene Therapeutics: Methods and Applications of Direct Gene Transfer cover
  • ISBN: 9780817636500
  • ISBN10: 0817636501

Gene Therapeutics: Methods and Applications of Direct Gene Transfer

by Wolff, J. A. A Wolff, Jon A.

  • List Price: $119.00
  • Binding: Hardcover
  • Publisher: Birkhauser Boston
  • Publish date: 04/01/1995
  • ISBN: 9780817636500
  • ISBN10: 0817636501
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Description: I Background.- A History of Gene Transfer and Therapy.- Producing Mouse Genetic Models for Human Diseases.- Post-Transcriptional Considerations of Gene Expression: Translation, MRNA Stability, and Poly(A) Processing.- Promoters, Enhancers, and Inducible Elements for Gene Therapy.- II Methods and Mechanisms.- Possible Mechanisms of DNA Uptake in Skeletal Muscle.- Receptor-Mediated Gene Delivery Employing Adenovirus-Polylysine-DNA Complexes.- Gene Transfer in Mammalian Cells Using Liposomes as Carriers.- In Vivo Gene Therapy via Receptor-Mediated DNA Delivery.- Calcium Phosphate-Mediated DNA Transfection.- Cellular Internalization of Oligodeoxynucleotides.- Gene Transfer via Particle Bombardment: Applications of the Accell Gene Gun.- Electrically-Induced DNA Transfer Into Cells. Electrotransfection In Vivo.- III Applications.- Pharmacokinetic Considerations in the Use of Genes as Pharmaceuticals.- Virus-Mediated Genetic Treatment of Rodent Gliomas.- Gene Therapy for Adenosine Deaminase Deficiency and Malignant Solid Tumors.- Development of Herpes Simplex Virus Vectors for Gene Transfer to the Central Nervous System.- Direct Gene Transfer and Catheter Based Gene Delivery Systems: Applications to Cardiovascular Diseases and Malignancy.- Gene Therapy for Arthritis.- Gene Therapy: The Advent of Adenovirus.- In Vivo Gene Transfer Into the Heart.- Receptor-Mediated Targeted Gene Delivery Using Asialoglycoprotein-Polylysine Conjugates.- Retroviral-Mediated Gene Transfer and Duchenne Muscular Dystrophy.- Keyword Index.
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Sewn binding. Cloth over boards. 417 p. Audience: General/trade. F40A
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Sewn binding. Cloth over boards. 417 p. Audience: General/trade. F40A
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