Description: 1 Monoclonal Antibodies to Human Tumor Antigens.- 1. Introduction.- 2. Monoclonal Antibodies to Preselected Antigens--Technology.- 3. Monoclonal Antibodies to Human Tumors.- 4. Potential Diagnostic and Therapeutic Uses of Monoclonal Antibodies.- 5. Potential Problems with Monoclonal Antibody Usage.- 6. Final Comments.- References.- 2 Cell Surface Antigens on Normal and Neoplastic Human Lymphoid Cells.- 1. Three Major Classes of Immunocompetent Lymphocytes.- 2. Cell Surface Markers Defined by Monoclonal Antibodies.- 3. Clinical Applications.- 4. Summary.- References.- 3 An Immunochemical Approach to the Isolation of Human Melanoma-Associated Antigens.- 1. Introduction.- 2. Methods.- 3. Identification of MAA in Spent Culture Medium.- 4. Characterization of Melanoma-Associated Antigens.- 5. Preparation of Specific Antimelanoma Xenoantisera to 240K and 94K Antigens.- 6. Purification of 240K and 94K MAA from Spent Culture Medium.- 7. Summary.- References.- 4 Skin Tumor Markers.- 1. Introduction.- 2. Melanoma.- 3. Basal- and Squamous-Cell Carcinoma.- 4. Conclusion.- References.- 5 Gastrointestinal Cancer Markers.- 1. Introduction.- 2. Enzymes and Hormones in Gastrointestinal Tumor Disease.- 3. Tissue Antigens of Human Gastrointestinal Cancers Defined by Xenogeneic Antisera.- 4. Tissue Antigens of Human Large Bowel Cancers Immunogenic in the Host of Origin.- 5. Tissue Antigens of Rat Bowel Cancers.- 6 Hepatocellular Carcinoma Markers.- 1. Introduction.- 2. Liver Function Tests.- 3. Alphafetoprotein.- 4. Enzymes and Isoenzymes.- 5. Systematic Manifestations of Hepatoma and Ectopic Hormone Production.- 6. Ferritin.- 7. Hepatoma-Associated Antigens.- 8. Hepatitis B Virus.- 9. Summary.- References.- 7 Pancreatic Tumor Markers.- 1. Introduction.- 2. Pancreatic Oncofetal Antigen.-3. Comparison with Carcinoembryonic Antigen.- References.- 8 Prostote Cancer Markers.- 1. Introduction.- 2. Prostatic Acid Phosphatase.- 3. Prostate Antigen.- 4. Alkaline Phosphatase.- 5. Ribonuclease.- 6. Polyamines.- 7. Conclusions.- References.- 9 Breast Cancer Markers.- 1. Introduction.- 2. Structure of the Breast.- 3. Diseases of the Breast.- 4. Oncodevelopmental Markers.- 5. Differentiation Markers.- 6. Other Tumor-Associated Molecules.- 7. Candidate Tumor-Specific Markers.- 8. Immune Response Markers.- 9. Genetic Markers.- 10. Comment.- References.- 10 Ovarian and Uterine Cancer Markers.- 1. Oncodevelopmental Antigens.- 2. Enzymes.- 3. Other Antigens.- 4. Summary.- References.- 11 Testicular Cancer Markers.- 1. Introduction.- 2. Clinical Aspects of Testicular Cancer.- 3. Incidence and Specificity of AFP and HCG.- 4. Markers as Aids in Diagnosis and Staging.- 5. Markers in Monitoring and Followup.- 6. Markers in Seminoma.- 7. Other Uses of AFP and HCG in Testicular Cancer.- 8. Other Markers for Testicular Cancer.- 9. Location of Tumors with Oncodevelopmental Markers.- 10. Tumor Markers in Pathology.- 11. The Future.- References.- 12 Placental Proteins as Tumor Markers.- 1. Introduction.- 2. Placental Alkaline Phosphatase.- 3. Histaminase (Diamine Oxidase).- 4. Human Chorionic Gonadotropin.- 5. Pregnancy Specific Glycoprotein (SP1).- 6. Placental Proteins (PP1).- 7. Final Remarks.- References.- 13 Bladder and Renal Tumor Markers.- 1. Introduction.- 2. Bladder Cancer.- 3. Renal Cancer.- References.- 14 Endocrine Markers of Cancer: The Biological and Clinical Implications of Polypeptide Hormones.- Geoffrey Mendelsohn, Stephen B. Baylin.- 1. Introduction.- 2. Patterns of Inappropriate (Ectopic) Hormone Production by Tumors.- 3. Proposed Mechanisms of Inappropriate Hormone Production by Non-Endocrine Tumors.- 4. Markers in Endocrine Tumors.- 5. Markers in Non-Endocrine Tumors.- 6. Summary.- References.- 15 Lung Cancer Markers.- 1. Introduction.- 2. Oncofetal Proteins.- 3. Hormones.- 4. Serum Proteins.- 5. Enzymes.- 6. Other Substances.- Tennessee Antigen (TA).- References.- 16 Central Nervous System Tumor Markers.- 1. Introduction.- 2. Markers of Primary Intracranial Tumors.- 3. Markers of Metastatic Intracranial Tumors.- 4. Conclusion.- 5. Future Prospects.- References.

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