Description:
Matrix Metalloproteinase Protocols is the first comprehensive collection of protocols specific for this field, and reviews protocols that are important in research on a growing family of proteolytic enzymes, the matrix metalloproteinases (MMPs) and the tissue inhibitors of metalloproteinases (TIMPs). It covers much of the methodology appropriate for the detection and assay of these proteins, as well as their expression and purification. MMPs and TIMPs are implicated in many physiological and pathological situations where the extracellular matrix is turned over or degraded, so that they represent important therapeutic targets in a number of diseases. This book will enable laboratories to have a wide range of relevant techniques right at their fingertips, while at the same time provide novice researchers with a starting point for their work and broaden the methods available to established groups. The wealth of knowledge and experience provided are invaluable, since they provide working methodologies that have been perfected over time from some of the best MMP labs in the world. For this reason they represent important therapeutic targets in a number of diseases. This book provides laboratories with a wide range of relevant techniques to serve as a springboard for their work and broaden the established repertoires of experienced researchers.
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Returnable at the third party seller's discretion and may come without consumable supplements like access codes, CD's, or workbooks.

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