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Mechanisms of Synaptic Transmission Bridging the Gaps (1890-1990)

by Joseph D. Robinson

  • ISBN: 9780195137613
  • ISBN10: 0195137612

Mechanisms of Synaptic Transmission Bridging the Gaps (1890-1990)

by Joseph D. Robinson

  • List Price: $94.00
  • Binding: Hardcover
  • Publisher: Oxford Univ Pr
  • Publish date: 05/01/2001
  • ISBN: 9780195137613
  • ISBN10: 0195137612
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Description: This book describes a century of research on how nerve cells communicate with one another, beginning with the formulation of the Neuron Theory and proceeding through studies embracing a broad range of disciplines. The Neuron Theory initially depicted discrete nerve cells interacting at their points of contact ("synapses"); since nerve impulse were often indentified as electrical signals traveling along neuronal processes, it seemed plausible that impulses would alsopass from cell to electrically. Over the next hundred years, however, ingenious experiments, facilitated by powerful new techniques and interpreted with imaginative new insights, established new accounts rich in scientific detail: communication was generally achieved by releasing chemicals from oneneuron to interact with specific receptors on another, thereby initiating complex chains of metabolic alterations as well as eliciting electrical responses; neurotransmitters were stored in vesicles for release onto postsynaptic neurons, and transport back into presynaptic neurons terminated the actions of some neurotransmitters whereas metabolic degradation terminated the actions of others. The formation of specific synapses during embryological development and the alterations in synaptictransmission accompanying learning also required intricate chains of cellular modifications. Disorders of synaptic transmission could result in neurological and psychiatric diseases, whereas drugs affecting particular steps in synaptic transmission could achieve dramatic therapeuticresponses.
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Product notice Returnable at the third party seller's discretion and may come without consumable supplements like access codes, CD's, or workbooks.
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8vo-over 7¾"-9¾" tall. 451 pp. Tightly bound. Corners not bumped. Text is free of markings.
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0195137612. 1.26 x 9.37 x 6.46 Inches; 472 pages.
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ISBN 0-19-513761-2 Octavo (9.5 in. by 6.5 in. ); 451pp.; fine hardcover; fine dust jacket; crisp; clean; bright. Three copies of this book are available.
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ISBN 0-19-513761-2 Octavo (9.5 in. by 6.5 in. ); 451pp.; fine hardcover; fine dust jacket; crisp; clean; bright. Three copies of this book are available.
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Good condition. Good dust jacket. (Medicine, Neurology, Reference) A copy
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