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  • ISBN: 9780122741203
  • ISBN10: 012274120X

Medicinal Chemistry: the Role of Organic Chemistry in Drug Research

by Ganellin, C. R. E Roberts, S. M.

  • List Price: $104.95
  • Binding: Hardcover
  • Edition: 0002
  • Publisher: Academic Press
  • Publish date: 02/01/1993
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Description: 1. Introduction to Receptors and the Action of Drugs 2. Structure and Atalytic Properties of Enzymes 3. Receptor Pharmacology 4. Drug Access and Prodrugs 5. QSAR and the Role of Computers in Drug Design 6. The Current Status and Future Impact of Molecular Biology in Drug Discovery 7. General Approaches to Discovering New Drugs: An Historical Perspective. 8. Discovery and Development of Cromakalim and Related Potassium Channel Activators 9. Angiotension-Converting Enzyme (ACE) inhibitors and the Design of Cilazapril 10. Beta Blockers 11. Salbutamol: A Selective B2-Stimulant Bronchodilator 12. Discovery of CCimetidine, Ranitidine and Other H2-Receptor Histamine Antagonists 13. Fluconazole, An Orally Active Antifungal Agent 14. Clavulanic Acid and Related Compounds: Inhibitors of B-Lactamase Enzymes
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