Error title
Some error text about your books and stuff.
Close

Multiple Drug Resistance in Cancer 2 Molecular, Cellular and Clinical Aspects

by Martin Clynes

  • ISBN: 9780792352723
  • ISBN10: 0792352726

Multiple Drug Resistance in Cancer 2 Molecular, Cellular and Clinical Aspects

by Martin Clynes

  • Binding: Hardcover
  • Edition: 0002
  • Publisher: Kluwer Academic Pub
  • Publish date: 03/01/1999
  • ISBN: 9780792352723
  • ISBN10: 0792352726
new Add to Cart $247.93
FREE economy shipping!
Description: Resistance to chemotherapy, and especially multi-drug resistance, represents a significant barrier to the successful treatment of cancer. This multi-author volume brings together a wide range of up-to-date reviews on different aspects of our knowledge of drug-resistance mechanisms, written by experts in the different areas. Particular attention is paid to recently discovered mechanisms relating to oncogene expression and in particular to proteins involved in regulation and execution of apoptosis. Other important topics covered include DNA repair, topoisomerases, cell cycle control, oxygenation and vascularization of tumors, LRP, intermediate filament proteins and low-level resistance. Recent developments in understanding the role of efflux pumps (P-170, MRP) in multi-drug resistance are also reviewed. This book will be useful to clinicians and scientists working in the areas of chemotherapy, drug resistance, DNA repair and apoptosis research.
Expand description
please wait
Please Wait

Notify Me When Available

Enter your email address below,
and we'll contact you when your school adds course materials for
.
Enter your email address below, and we'll contact you when is back in stock (ISBN: ).