Description: Foreword. Preface. Part I: Fundamental Issues in Clinical Metrology. 1. The Evolution of Assessment Techniques. 2. Reliability. 3. Validity. 4. Responsiveness. 5. Scaling Options. 6. Weighting and Aggregation. 7. Reporting, Application and Utilization. Part II: Unidimensional and Multidimensional Outcome Measures. 8. Pain Measurement. 9. Health Status Instruments and Functional Indices. 10. Articular Indices. 11. Mechanical and Electromechanical Devices. 12. Composite Indices. Part III: Current Clinimetric Practices in Musculoskeletal Clinical Trials. 13. Rheumatoid Arthritis. 14. Osteoarthritis. 15. Ankylosing Spondylitis. 16. Fibromyalgia. Part IV: Clinical Applications and Implications. 17. Standardised Procedures for Outcome Measurement and Parameters for Calculating Sample Size for Antirheumatic Drug Studies. 18. Future Perspective. Appendix A: Functional Indices and Health Status (1937-1992). Appendix B: Standard Deviation Tables for Sample Size Calculation in Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis and Fibromyalgia Clinical Trials. Appendix C: Estimated Sample Size Requirements for Clinical Trials in Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis and Fibromyalgia. Index.

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