Description: Synthesis of Polyampholyte Comb-Type Copolymers Consisting of a Poly(L-lysine) Backbone and Hyaluronic Acid Side Chains for DNA Carrier.- Cationic ?-Helical Peptides for Gene Delivery into Cells.- Supramolecular Self-Assembly of Poly(ethylene glycol)-Block-Poly (L-lysine) Dendrimer with Plasmid DNA.- Water-Soluble Cationic Methacrylate Polymers for Nonviral Gene Delivery.- Stabilization of Polycation-DNA Complexes by Surface Modification with Hydrophilic Polymers.- Use of Disulfide Cationic Lipids in Plasmid DNA Delivery.- Interactions of Lipid-Oligonucleotide Conjugates with Low-Density Lipoprotein.- Coupling of Nuclear Localization Signals to Plasmid DNA.- Progress Toward a Synthetic Virus.- Characterization of Polyampholyte Comb-Type Copolymer DNA Carriers.- Methods for Studying the Formation of Polycation-DNA Complexes and Properties Useful for Gene Delivery.- Characterization of DNA Condensates by Atomic Force Microscopy.- Rapid and Systematic Transfer and Recovery of Large BACs/PACs into Mammalian Cells by HAEC Retrofitting.- Systemic Delivery of Therapeutic Proteins by Intramuscular Injection of Plasmid DNA.- Local Delivery of Therapeutic Proteins by Intratumoral Injection of Plasmid DNA-Lipid Complexes.- Nonviral DNA Delivery from Polymeric Systems.- Promotion of Duplex and Triplex DNA Formation by Polycation Comb-Type Copolymers.- Lyophilization of Nonviral Gene Delivery Systems.- Ultraviolet Absorption and Circular Dichroism Spectroscopy of Nonviral Gene Delivery Complexes.- Characterization of Synthetic Gene Delivery Vectors by Infrared Spectroscopy.- Characterization of Cationic Vector-Based Gene Delivery Vehicles Using Isothermal Titration and Differential Scanning Calorimetry.- Light-Scattering Techniques for Characterization of Synthetic Gene TherapyVectors.- Renal Gene Therapy.

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