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  • ISBN: 9780121461607
  • ISBN10: 0121461602

Nuclear Receptors and Genetic Disease

by Thomas P. Burris

  • List Price: $280.00
  • Binding: Hardcover
  • Publisher: Academic Pr
  • Publish date: 09/01/2000
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Description: Nuclear Receptors and Genetic Disease provides the first compilation of the role of nuclear hormones in health and disease and incorporates the latest breakthroughs in the field. It provides comprehensive reviews of the major receptors prepared by the acknowledged experts in each area. Structured for ease of reference, each chapter provides information on the history, physiology, structure, mechanism of action, genetics, pathophysiology, disease diagnosis, and disease treatment for a particular nuclear receptor. A comprehensive list of mutations for each receptor detailing localization, biochemical phenotype and clinical phenotype is also included.

Nuclear Receptors and Genetic Disease offers a unique perspective, focusing on the molecular biology of nuclear receptor action and its relationship to pathophysiology. It is essential reading for both basic and clinical scientists in the field of endocrinology, biochemistry, molecular biology, cell and developmental biology, and gene expression. It will also be of key interest to those working in pharmacology and reproductive biology, clinicians in endocrinology, clinical genetics, oncology, obstetrics and gynecology.

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