Howe's theme is the exile of the spirit in this world and the painfully exciting, tiny margin in which movement out of exile is imaginable and perhaps possible. Her best poems are simultaneously investigations of that possibility and protests against the difficulty of salvation.

Boston is the setting of some of the early poems, and Ireland, the birthplace of Howe's mother, is the home of O'Clock, a spiritually piquant series of short poems included in Selected Poems.

The metaphysics and the physics of this world play off each other in these poems, and there is a toughness to Howe's unique, fertile nervousness of spirit. Her spare style makes a nest for the soul:

Zero built a nest

in my navel. Incurable

Longing. Blood too --

From violent actions

It's a nest belonging to one

But zero uses it

And its pleasure is its own