Description: Teratogenic exposures during embryonic or fetal life can produce permanent abnormalities of structure or function. Although the number of individuals affected is relatively small -- perhaps accounting for about one-tenth of all birth defects -- teratogenic exposures are nevertheless important because they are potentially preventable. In Teratogenic Effects of Drugs, J. M. Friedman, M.D., Ph.D., and Janine E. Polifka, Ph.D., present an updated version of their catalog for clinicians.

With more than 1,100 agent summaries, this new edition expands the clinically oriented information now available on the potential teratogenic effects of drugs and other agents on the developing fetus or embryo. Unique to this catalog is a rating system by which an internationally recognized panel of teratologists assesses the risk associated with usual exposures to each agent. Also rated are the quality and quantity of data upon which the panel's assessment is based. Each entry includes a concise narrative summary that-reviews the available information as well as a list of key references.

Terotogenic Effects of Drugs is the hardcover version of a computerized database known as the Teratogen Information System (TERIS), the on-line version of which first appeared in 1987. This new edition will continue to serve as a reference for use by clinical and research geneticists, teratologists, obstetricians, and pediatricians.

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