Description: Toxicity Assessment Alternatives contains a broad array of critical surveys, including two dozen state-of-the-art reports on alternatives to toxicity assessment from internationally respected research scientists and investigators. It provides current information on recent developments on mechanically-based alternatives, current trends and future projections, hazard assessment applications, and the validation of alternatives. This book provides information from various scientific and regulatory communities on newly achieved and accepted alternatives to animal testing, such as the use of transgenic models that reduce the time and cost of carcinogenicity testing, the use of tissue cultures for the assessment of endocrine-disrupting chemicals, and the application of molecular modeling to explain chemical toxicity.

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