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Tumor Supressor Genes in Cancer Therapy

by David E. Fisher

  • ISBN: 9780896038073
  • ISBN10: 0896038076

Tumor Supressor Genes in Cancer Therapy

by David E. Fisher

  • List Price: $299.00
  • Binding: Hardcover
  • Publisher: Humana Pr Inc
  • Publish date: 11/01/2000
  • ISBN: 9780896038073
  • ISBN10: 0896038076
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Description: This book covers the clinical and experimental observations that led to tumor suppressor gene discovery as well as detailed mechanistic reviews of tumor suppressor genes whose actions are understood. Many of these genes relate specifically to cancer therapy and the focus on mechanistic insights and therapeutic strategies are emphasized. Through the detailed presentation of tumor suppressor genes with a molecular biological and genetic perspective, several paradigms emerge: 1) a finite number of discrete pathways exist into which tumor suppressors and dominant oncogenes reside, and 2) cancer biology rests heavily on regulators of both cell proliferation and cell death.
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